Endocrine Abstracts

Introduction: COVID-19 is a novel pandemic affecting globally. It has led to an unprecedented global health crisis assessing health system’s preparedness to deal with health disasters. The aim of our study was to evaluate the impact of COVID-19 on the follow up care of diabetic patients.Methods: We conducted a retrospective study in 100 insulin-requiring diabetic patients. Data regarding treatment availability, weigh, glycemic control and follow up ...

Introduction: Hemochromatosis is associated with iron overload that is responsible of iron deposit causing multiple organ dysfunctions which affects especially endocrine glands.Methods: We report four cases of pituitary hemochromatosis responsible of endocrine dysfunction. Results: Three women and one man were included, aged respectively 28, 19, 26 and 35 years old. These patients were suffering from ß-thalassemia and treated ...

Background: Insulinoma is a rare variety of endocrine neoplasm and is usually benign, solitary, and small in size. It is responsible of endogenous insulin secretion resulting in development of symptoms of hypoglycemia.Case presentation: We report 4 cases of insulinoma that were diagnosed and managed in the year 2022. Three women and one man aged respectively 76, 68, 60 and 42 years-old. All patients presented a long history of various adrenergic symptoms...

Introduction: The insulinoma is a rare neuroendocrine tumor derived from the beta islet cell of the pancreas. It is usually sporadic and benign in 90% of the cases. It occurs more often in women in their fifties.Observation: We report the case of 76-year-old women with a medical history of hypertension and dyslipidemia, who was transferred to our department from the emergency unit after a diagnosis of severe episode of hypoglycemia (glucose level at 0.2 ...

Background: Adrenocortical carcinoma is a rare malignancy with a poor prognosis. Local recurrence is affected by the pathologic features (tumor staging and mitotic index) and the complete surgical resection. Treatment of a recurrent adrenocortical carcinoma can be a real challenge.Case description: We report a case of 47-year-old man who was operated for an adrenal tumor with bone metastases. Left adrenalectomy and splenectomy were performed and histolog...

Background: Wolfram syndrome is an autosomal recessive neurodegenerative disease. It is secondary to the mutation of WFS1 gene. It combines a tetrad of pathologies known also as DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness). Case presentation: We report a case of 31-year-old women with medical history of type 1 diabetes since the age of 3 years old. She suffered from decreased visual acuity since the age of 5 years old and t...

Introduction: Thyrotropin-secreting pituitary tumors (TSH-omas) are a rare cause of hyperthyroidism and account for 0.5 to 3 percent of all functioning pituitary tumors and much less than 1 percent of all cases of hyperthyroidism. The co-secretion of thyrotropin (TSH) and growth hormone (GH) in pituitary adenoma is extremely rare. Only a few cases have been reported.Observation: We report the case of a 40-year-old man who consulted an ophthalmologist for...

Background: Multiple endocrine neoplasia (MEN) are rare and are characterized by the association of a neoplasia or hyperplasia of at least two endocrine glands. Rare cases of atypical MEN were reported in the literature. We describe a rare combination of acromegaly, papillairy thyroid carcinoma and primary hyperaldosteronism.Case presentation: We report a case of a 48-year old woman operated for papillary thyroid carcinoma. Five years later, sh...

Introduction: Androgenic insensitivity syndrome (AIS) is an X-linked genetic disease characterized by resistance to the actions of androgen in an individual with 46, XY karyotype. It is the most common cause of DSD in 46, XY individuals.Case report: We report a case of a 16-year-old girl who consulted for primary amenorrhea and hirsutism. Our patient had a 9-year-old sister who was operated for an inguinal hernia and the anathomopathological study conclu...